Tamoxifen liver damage

Discussion in 'Best Price Prescription Drugs' started by NNew, 15-Sep-2019.

  1. kor2006 New Member

    Tamoxifen liver damage


    Diane E wrote: I had labs drawn yesterday for my onc check up. Previous labs done were in December and they were fine. My AST and ALT are now elevated at 83 and 76, up from 36 and 32 in December. I see the onc today but already had a heads up from the Nurse Practioner that he is going to recheck them in a week and see what happens before doing a liver ultrasound. I hope it is the tamoxifen, but that really cuts down on years of meds available for ER and the ovaries would need to come out. I guess it is a small price to pay if he can tell me I am still NED. I did have a PET/CT in December that was negative and he told the NP he took great comfort in having that info. Diane Apr 30, 2009 PM jpann39 wrote: Diane I was told from the get go that Tamox is known to raise those #'s..... Well, I had inflammatory breast ca, so I have to get past the fact that 4 months is plenty of time for everything to rear its ugly head. I just did a 12 hr fasting blood draw and will see my doctor this coming week so will see what it has done to my numbers as Ive been on it over 2 years and had slightly high cholestrol to begin with. Best wishes Jule Apr 30, 2009 PM desdemona222b wrote: I had the same problem, but my liver enzymes were much higher than that - more like around 156 or something. WRSH Partner, Phil Russotti, represented a 55 year old woman who was taking Tamoxifen following a radical mastectomy for breast cancer and who suffered liver failure requiring a liver transplant. After approximately nine months on the Tamoxifen she reported to her doctor, who was prescribing the medication that she was noticing fatigue. We claimed that her doctor should have ordered a liver function study. Three months later a subsequent treating doctor ordered liver function tests which were elevated. This second doctor failed to follow up on the elevated liver function studies, one month afterward she became jaundiced and shortly thereafter suffered acute liver failure resulting in the liver transplant. We claimed that the Tamoxifen should have been immediately discontinued when the liver study was abnormal which would have prevented the liver failure. Defendant claimed that the New York equivalent of Dalbert namely, the Frye requirement of scientific proof on the issue of causation had not been established showing a relationship between Tamoxifen and liver failure. The client has not had any difficulties with her transplanted liver for the past ten years.

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    When liver damage is caused by chemicals. Some treatments for breast cancer can affect how your liver functions chemotherapy; tamoxifen, a hormonal therapy; Google Tamox and liver damage. Of course it's know to cause liver damage! This is from the tamoxifen drug literature "Tamoxifen has been associated with changes in liver enzyme levels, and on rare occasions, a spectrum of more severe liver abnormalities including fatty liver, cholestasis, hepatitis and hepatic necrosis. Full text Full text is available as a scanned copy of the original print version. Get a printable copy PDF file of the complete article 220K, or click.

    Your order will be packed safe and secure and dispatched within 24 hours. This is exactly how your parcel will look like (pictures of a real shipping item). It has a size and a look of a regular private letter (9.4x4.3x0.3 inches or 24x11x0.7cm) and it does not disclose its contents I prefer not to take generics of Nolvadex if I can buy the original Nolvadex online from the certified company. The seller cares about its name and image and makes a quick delivery. As for me, I also prefer the original rather than analogues of the same drug. The principles of effectiveness are different, and there might be more side effects. I take Nolvadex only online, as I already trust the company, and they deliver it without any problems. I was afraid of side effects of Nolvadex, but, actually, I didn’t face them at all. I’ve been taking Nolvadex for a few months, and it has a good effect on me. My sister in low has a early stage breast cancer and is taking tamoxifen pills. I was doing some research on the net and found out that tamoxifen can cause liver cancer. What is the connection between tamoxifen and liver cancer ? It is not known Tamoxifen to cause liver cancer in humans. I would be careful while on Tamoxifen and make sure to have tests done to monitor how this drug is affecting your body. Sometimes it can cause other liver toxicities in patients, which can be severe or life threatening. Another women I know who took Tamoxifen also for 5 years, had to have a hysterectomy due to suspicious changes in her uterus. Blood tests are usually performed from time to time to check liver function. I think there needs to be more research on this drug. I'm sure your sister in low will find Tamoxifen beneficial. My mother took part in a tamoxifen trial in the UK. There are clinical evidences, about tamoxifen used as adjuvant therapy for early stage breast cancer, that showed reduced risk of recurrence of the original cancer and also reduced risk of developing new cancers in the other breast. My mother was taking Tamoxifen for 5 years after having breast cancer. She had had a very early stages lump removed from one breast with an excellent prognosis as it was such early stages. Anyway, she agreed to take part in a 5 year tamoxifen trial.

    Tamoxifen liver damage

    Tamoxifen-induced fatty liver in patients with breast cancer., Does Tamoxifen Cause Liver Cancer - eHealth Forum

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  5. Protective role of thymoquinone against liver damage induced by tamoxifen in female rats. Ghada M. Suddek. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.

    • Protective role of thymoquinone against liver damage induced..
    • Tamoxifen and liver damage. - PubMed Central.
    • Tamoxifen and liver damage - Generation Success.

    Clinically apparent, acute liver injury due to tamoxifen. Modified from Blackburn AM, Amiel SA, Millis RR, Rubens RD. Tamoxifen and liver damage. Br Med J. Tamoxifen is associated with blood clots leading to deep vein thrombosis and pulmonary embolism. Tamoxifen can cause abnormalities of liver tests, reduced white blood cells, red blood cells, and platelets. Reduced platelets can lead to bleeding. I have been on Tamoxifen for 1 year now following 4 chemo treatments and radiation for a ER positvie tumor. My most recent Dr. visit revealed elevated liver function.

     
  6. borso New Member

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