Azithromycin in pregnancy

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  1. adone Moderator

    Azithromycin in pregnancy


    It's widely used to treat chest infections such as pneumonia, infections of the nose and throat such as sinus infection (sinusitis), skin infections, Lyme disease, and some sexually transmitted infections. Azithromycin is used in children, often to treat ear infections or chest infections. It can also be used long term to prevent chest infections in people who keep getting them. The medicine is available on prescription as capsules, tablets and a liquid that you drink. It can also be given by injection, but this is usually only done in hospital. Azithromycin is usually taken once a day, unless you're having it by injection. Try to take your medicine at the same time each day. 500 mg PO once, then 250 mg once daily for 4 days 2 g extended release suspension PO once 500 mg IV as single dose for at least 2 days; follow with oral therapy with single dose of 500 mg to complete 7-10 days course of therapy Infection of pharynx, cervix, urethra, or rectum: Ceftriaxone 250 mg IM once plus azithromycin 1 g PO once (preferred) or alternatively doxycycline 100 mg PO q12hr for 7 days CDC STD guidelines: MMWR Recomm Rep. June 5, 20(RR3);1-137 Agitation Allergic reaction Anemia Anorexia Candidiasis Chest pain Conjunctivitis Constipation Dermatitis (fungal) Dizziness Eczema Edema Enteritis Facial edema Fatigue Gastritis Headache Hyperkinesia Hypotension Increased cough Insomnia Leukopenia Malaise Melena Mucositis Nervousness Oral candidiasis Pain Palpitations Pharyngitis Pleural effusion Pruritus Pseudomembranous colitis Rash Rhinitis Seizures Somnolence Urticaria Vertigo Anaphylaxis Angioedema Anorexia Bronchospasm Constipation Dermatologic reactions Dyspepsia Elevated liver enzymes Erythema multiforme Flatulence Oral candidiasis Pancreatitis Pseudomembranous colitis Pyloric stenosis, rare reports of tongue discoloration Stevens-Johnson syndrome Torsades de pointes Toxic epidermal necrolysis Vomiting/diarrhea, rarely resulting in dehydration Neutropenia Elevated bilirubin, AST, ALT, BUN, creatinine Alterations in potassium Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Use with caution in abnormal liver function, hepatitis, cholestatic jaundice, hepatic necrosis, and hepatic failure have been reported, some of which have resulted in death; discontinue azithromycin immediately if signs and symptoms of hepatitis occur Injection-site reactions can occur with IV route In treatment of gonorrhea or syphilis, perform susceptibility culture tests before initiating azithromycin therapy; may mask or delay symptoms of incubating gonorrhea or syphilis. Bacterial or fungal superinfection may result from prolonged use Prolonged QT interval: Cases of torsades de pointes have been reported during postmarketing surveillance; use with caution in patients with known QT prolongation, history of torsades de pointes, congenital long QT syndrome, bradyarrhythmias, or uncompensated heart failure; also use with caution if coadministering with drugs that prolong QT interval or proarrhythmic conditions (eg, hypokalemia, hypomagnesemia); elderly patients may be more susceptible to drug-associated effects on QT interval Pneumonia: PO azithromycin is safe and effective only for community-acquired pneumonia (CAP) due to C pneumoniae, H influenzae, M pneumoniae, or S pneumoniae Cases of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) reported; despite successful symptomatic treatment of allergic symptoms, when symptomatic therapy was discontinued, allergic symptoms recurred soon thereafter in some patients without further azithromycin exposure; if allergic reaction occurs, the drug should be discontinued and appropriate therapy instituted; physicians should be aware that allergic symptoms may reappear when symptomatic therapy discontinued Endocarditis prophylaxis: Indicated only for high-risk patients, per current AHA guidelines Use caution in renal impairment (Cr Cl Because of the low levels of azithromycin in breastmilk and use in infants in higher doses, it would not be expected to cause adverse effects in breastfed infants (Lact Med; https://nih.gov/newtoxnet/lactmed.htm) Binds to 50S ribosomal subunit of susceptible microorganisms and blocks dissociation of peptidyl t RNA from ribosomes, causing RNA-dependent protein synthesis to arrest; does not affect nucleic acid synthesis Concentrates in phagocytes and fibroblasts, as demonstrated by in vitro incubation techniques; in vivo studies suggest that concentration in phagocytes may contribute to drug distribution to inflamed tissues Y-site: Amikacin, aztreonam, cefotaxime, ceftazidime, ceftriaxone, cefuroxime, ciprofloxacin, clindamycin, droperidol, famotidine, fentanyl, furosemide, gentamicin, imipenem, cilastatin, ketorolac, levofloxacin, morphine, piperacillin-tazobactam, ondansetron(? ), potassium chloride, ticarcillin-clavulanate, tobramycin The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

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    Medscape - Infection-specific dosing for Zithromax, Zmax azithromycin, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Chlamydial Infections in Adolescents and Adults. Chlamydial infection is the most frequently reported infectious disease in the United States, and prevalence is highest in persons aged ≤24 years. Several sequelae can result from C. trachomatis infection in women, the most serious of which include PID, ectopic pregnancy, and infertility. Some. Azithromycin oral tablet is used to treat infections caused by bacteria. It's a prescription medication that's available as a generic drug and as the brand-name drug.

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    Azithromycin in pregnancy

    Azithromycin in pregnancy - -., Chlamydial Infections - 2015 STD Treatment Guidelines

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  6. Pregnancy Considerations Adverse events were not observed in animal studies; therefore, azithromycin is classified as pregnancy category B. Azithromycin crosses the placenta. Fetal malformations have not been observed following maternal use of azithromycin.

    • Azithromycin pregnancy category - MedHelp.
    • Azithromycin Side Effects, Dosage, Uses, and More.
    • Azithromycin antibiotic to treat bacterial infections - NHS.

    Taking Azithromycin During Pregnancy, What You Should Know About Taking Azithromycin in Pregnancy. No harm has been found with its use during pregnancy. Its safety during breastfeeding is not confirmed, but it is likely safe. Azithromycin is an azalide, a type of macrolide antibiotic. It works by decreasing the production of protein, thus stopping bacterial growth. Azithromycin was first discovered in 1980. Clarithromycin and Azithromycin in Pregnancy. In a study published in the journal Pharmacoepidemiology and Drug Safety, researchers investigated whether there was any link between taking macrolides – including azithromycin and clarithromycin – during pregnancy and having a baby with birth defects.

     
  7. Borys Well-Known Member

    Wondering if it is safe to take cold medicine when you are pregnant? It’s natural to turn to the medicine cabinet at the first sign of a headache, indigestion or sniffle. But when you’re pregnant, you have to think twice about using over-the-counter (OTC) medication. Here are some of the most common drugs pregnant women must avoid and alternative methods of treatment. Aspirin, ibuprofen and naproxen, found in OTC medications like Excedrin Migraine, Aleve, Advil and Motrin, are common drugs that pregnant women simply cannot take, says Rebecca Kolp, associate director of gynecology at Massachusetts General Hospital. Also beware of caffeine – found in Excedrin Aspirin-Free and Excedrin Quicktabs. Consumer Reports recommends not exceeding 200 milligrams a day to reduce the risk of miscarriage. “The only over-the-counter pain medication that is safe in pregnancy is Tylenol (acetaminophen) used in prescribed doses,” says Kolp. Chinese herbalist and natural wellness specialist Aimee Raupp recommends rubbing peppermint oil on your temples and applying a cold compress on your forehead if you’re experiencing a migraine. Medications during pregnancy List of safe and unsafe Summer Elkhorn - Madison Classics Services Dream House
     
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    Azithromycin for Acute Bronchitis? - NEJM Journal Watch The use of antibiotics for treating acute bronchitis has been. improvements in health-related quality of life than does low-dose vitamin C.

    Dead People Don't Get Bronchitis — Thoughts on Zithromax.