I tried all kinds of methods and even some medications before I got my hands on Dapoxetine, and l was really excited when I heard about it. Yes, but it gives me about 3-4 extra minutes – something I’m not totally content with; I'm still holding out for something more effective and readily available.”“My boyfriend has always been overeager in bed. Medically speaking, he doesn’t have premature ejaculation because he can usually last as long as 5 minutes or so. Unfortunately, that’s not enough for me – need a bit more time to reach a climax. We tried Priligy a few times and it seems to help, but Lee (my boyfriend) says it gives him a slight headache. So he stopped using it for the time being.”“My doctor suggested I took Priligy on a trial basis after treating my PE for half a year with different methods and no notable result. I’ve tried the 60mg one hoping it will make me last even longer, but, surprisingly, it has just the same effect on me.”“Dapoxetine is one of those drugs that really have its pros and cons. I was a bit wary of the drug when I learned that it is essentially an antidepressant, but tried it anyway since you have to occasionally take just one pill before sexual intercourse. First of all, it works and just like other “male pills”, it can be taken “as needed” and its effect will kick in within a few hours. However, it also means you will need to take a pill every single time you plan to engage in sex, which is a bit inconvenient in general since you have to calculate when exactly you’ll have sex to take a pill two hours before that.”“I never knew what a long-lasting erection was before I was able to try dapoxetine, so I really can’t wait for it to become freely available in the US. Some of the views expressed in the following notes on newly approved products should be regarded as preliminary, as there may have been limited published data at the time of publication, and little experience in Australia of their safety or efficacy. However, the Editorial Executive Committee believes that comments made in good faith at an early stage may still be of value. Before new drugs are prescribed, the Committee believes it is important that more detailed information is obtained from the manufacturer's approved product information, a drug information centre or some other appropriate source. Approved indication: premature ejaculation Priligy (A Menarini) 30 mg tablets Australian Medicines Handbook section 13.3.2 Delayed ejaculation is an adverse effect of selective serotonin reuptake inhibitors (SSRIs) in men. Dapoxetine, a short-acting SSRI, is the first drug to be marketed for premature ejaculation. 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Purchase The mechanism of action of Priligy in premature ejaculation is associated with inhibition of the reuptake of serotonin by neurons, followed by an increase in the action of the neurotransmitter on pre- and postsynaptic receptors. The mechanism of ejaculation is regulated mainly by the sympathetic nervous system. Postganglionic sympathetic nerve fibers innervate the seminal vesicles, the vas deferens, the prostate, the urethra and the neck of the bladder, causing their coordinated contraction to achieve ejaculation. Dapoxetine is rapidly absorbed, and the maximum concentration in the blood plasma (Cmax) is reached 1-2 hours after taking the drug. The intake of fatty food moderately reduces Cmax of dapoxetine (by 10%) and increases by 12% the AUC and the time to reach the maximum concentration in the blood plasma. More than 99% of dapoxetine binds to plasma proteins. 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