Erythromycin 250 mg, 333 mg, 500 mg tablets, capsules; 2% topical solution; 2% gel; 2% ointment; 2% pledgets; 5% ophthalmic ointment; Erythromycin Estolate 250 mg capsules; 500 mg tablets; 125 mg/m L, 250 mg/m L suspension; Erythromycin Stearate 250 mg, 500 mg tablets Macrolide antibiotic produced by a strain of Streptomyces erythreus. Bacteriostatic or bactericidal, depending on nature of organism and drug concentration used. More active against gram-positive than gram-negative bacteria. Effectiveness against Chlamydia trachomatis is basis for its topical use in prophylaxis of neonatal inclusion conjunctivitis. Pneumococcal pneumonia, Mycoplasma pneumoniae (primary atypical pneumonia), acute pelvic inflammatory disease caused by Neisseria gonorrhoeae in females sensitive to penicillin, infections caused by susceptible strains of staphylococci, streptococci, and certain strains of Haemophilus influenzae. Also used in intestinal amebiasis, Legionnaires' disease, uncomplicated urethral, endocervical, and rectal infections caused by Chlamydia trachomatis, for prophylaxis of ophthalmia neonatorum caused by N. trachomatis, and for chlamydial conjunctivitis in neonates. Considered an acceptable alternative to penicillin for treatment of streptococcal pharyngitis, for prophylaxis of rheumatic fever and bacterial endocarditis, for treatment of diphtheria as adjunct to antitoxin and for carrier state, and as alternate choice in treatment of primary syphilis in patients allergic to penicillins. 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